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Updated: Aug 11, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Progress in cardiovascular disease: technical considerations in cardiac resynchronization therapy

Safwat A Gassis1, David B Delurgio, Angel R Leon

  • 1Carlyle Fraser Heart Center, Emory University School of Medicine, Atlanta, GA 30308, USA.

Progress in Cardiovascular Diseases
|March 7, 2006
PubMed

Insights

Cardiac resynchronization therapy (CRT) improves heart failure outcomes in patients with systolic dysfunction and conduction delays. Proper patient selection, implantation, and programming are crucial for optimal CRT benefits.

Area of Science:

  • Cardiology
  • Medical Devices

Background:

  • Cardiac resynchronization therapy (CRT) is indicated for patients with moderate to severe heart failure and ventricular dyssynchrony.
  • Ventricular dyssynchrony is often identified by a prolonged QRS duration on electrocardiogram.

Purpose of the Study:

  • To review the technical aspects of CRT implantation and device programming.
  • To guide clinicians in optimizing patient care and long-term response to CRT.

Main Methods:

  • This review synthesizes current knowledge on CRT implementation.
  • It focuses on practical considerations for patient preparation, complication surveillance, and device programming.

Main Results:

  • CRT can improve symptoms, ventricular function, and survival in selected heart failure patients.
  • Effective CRT requires meticulous attention to procedural technique and device optimization.

Conclusions:

  • Clinicians must possess comprehensive knowledge of CRT to ensure successful patient outcomes.
  • Optimizing CRT programming is essential for maximizing long-term therapeutic benefits.

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