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Updated: Aug 5, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
Traumatic optic neuropathy caused by blunt injury to the inferior orbital rim
Tomo Nishi1, Tetsuo Ueda, Eiichi Yukawa
1Department of Ophthalmology, Nara Medical University, Nara, Japan. ntomo24@r7.dion.ne.jp
Abstract:
A 48-year-old woman was struck on the right inferior orbital rim by a gardening device and immediately developed complete visual loss in the right eye. Clinical and imaging evaluations failed to disclose any damage to the globe or optic nerve or to their nearby soft tissues and bones. Within months, ipsilateral optic disc pallor, a nerve fiber bundle visual field defect, and a persistently subnormal visual acuity developed. We attribute the visual loss to indirect optic nerve injury. To our knowledge, blunt injury to the inferior orbital rim has not been reported as a cause of this phenomenon.
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