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Management of orbital metastases
U Schick1, O Lermen, W Hassler
1Neurochirurgische Klinik, Wedau Kliniken, Duisburg, Germany. Uta_Schick@web.de
Zentralblatt Fur Neurochirurgie
|March 7, 2006
Summary
Orbital metastases from cancers like lung and breast are rare but serious. Treatment requires a multidisciplinary approach, with outcomes often poor despite interventions.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Orbital metastases are uncommon, representing a rare manifestation of advanced cancer.
- Lung and breast cancers are the most frequent primary sites metastasizing to the orbit.
Purpose of the Study:
- To review the treatment and clinical outcomes of patients with orbital metastases.
- To analyze the characteristics and prognosis of orbital metastatic disease.
Main Methods:
- Retrospective analysis of 11 cases of orbital metastases treated between 1995 and 2002.
- Surgical approach tailored to lesion location and type.
- Review of primary cancer types, patient history, and treatment modalities.
Main Results:
- Lung and breast cancers were the most common primary tumors.
- Six patients had no prior cancer history; one primary site remained unknown.
- Three patients experienced tumor recurrence despite chemotherapy and/or radiotherapy.
- Mean survival time post-diagnosis of orbital metastasis was 15 months.
Conclusions:
- Orbital metastases indicate a poor systemic prognosis, necessitating a multidisciplinary treatment strategy.
- Therapeutic options encompass surgical interventions, chemotherapy, hormonal therapy, and radiation therapy.
