Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Cystic panfolliculoma.

Mai P Hoang¹, Brian M Levenson

¹Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9073, USA. mai.hoang@utsouthwestern.edu

Archives of Pathology & Laboratory Medicine

|March 8, 2006

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cutaneous Metastases of Unusual Tumor Types: Retrospective Single-Institution Analysis and Literature Review.

The American Journal of dermatopathology·2026

Same author

False negative rate of direct immunofluorescence in bullous pemphigoid does not significantly differ by anatomic site.

Journal of the American Academy of Dermatology·2026

Same author

Sarcomatoid Squamous Cell Carcinoma and Its Mimics: A Meta-Analysis of Institutional Cases and Published Reports.

Cancers·2026

Same author

Role of POU4F3 in the Diagnosis of Cutaneous Follicular Tumors.

Journal of cutaneous pathology·2026

Same author

Histologic Distinction Between Clear Cell Sarcoma and Melanoma Using Supervised and Deep Learning.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica·2026

Same author

Clinicopathologic and Immunohistochemical Features of Enfortumab Vedotin-Induced Cutaneous Toxicity.

International journal of dermatology·2026

This study describes a rare case of cystic panfolliculoma, a hair follicle tumor. Histological and immunohistochemical analysis revealed unique features of this scalp neoplasm.

Area of Science:

Dermatopathology
Oncology
Histology

Background:

Panfolliculoma is a rare neoplasm showing differentiation towards both upper and lower hair follicle segments.
Understanding its diverse presentations is crucial for accurate diagnosis.

Observation:

A 33-year-old woman presented with an 8-month history of a 3.0-cm cystic scalp mass.
The lesion was surgically excised for further examination.

Findings:

Histological examination revealed a cystic follicular neoplasm with characteristic features including corneocytes, trichohyalin granules, germinative cells, papillae, matrical cells, and "shadow" cells.
Immunohistochemical staining showed uniform highlighting of tumor cells by Cytokeratin 903 and Cytokeratin 5/6.
Ber-EP4 strongly labeled germinative cells, while CD34 highlighted the surrounding stroma.

Related Experiment Videos

Implications:

This case expands the understanding of cystic variations in panfolliculoma.
The distinct histological and immunohistochemical profile aids in differentiating it from other follicular tumors.
Further research into rare follicular neoplasms can improve diagnostic accuracy and patient management.