Related Experiment Videos
Retinal angiomatous proliferation treated by intravitreal triamcinolone and photodynamic therapy with verteporfin
Massimo Nicolò1, Davidina Ghiglione, Silvio Lai
1Dipartimento di Neuroscienze, Oftalmologia e Genetica, Sezione di Clinica Oculistica, Università di Genova, Osp. San Martino, Pad. 9, piano terra stanza 13. Largo R. Benzi 10, 16132, Genova, Italy. massimonicolo@occhioallaretina.it
Purpose:
To examine combined treatment of intravitreal triamcinolone acetonide (IVT) and photodynamic therapy (PDT) for retinal angiomatous proliferation (RAP).
Methods:
Ten eyes of eight consecutive patients with RAP underwent a single injection (about 20 mg) of IVT followed 1 month later by PDT. Best-corrected visual acuity (BCVA) was measured by standardized protocol refraction.
Results:
Median BCVA was 20/160, 20/64, 20/98, 20/89, 20/89, 20/125 at baseline and 1, 3, 6, 9 and 12 months, respectively. Of ten eyes, six (60%) improved BCVA of at least 3 lines at 1, 3, 6 and 9 months. Four (40%) eyes improved BCVA of at least 3 lines at 12 months. Three eyes (30%) lost >3 lines at 12 months. In all patients intraocular pressure was well controlled. No endophthalmitis, retinal detachment or vitreous haemorrhage developed.
Conclusions:
Improvement of BCVA suggests that combination treatment with IVT and PDT for RAP merits further investigation.
