Related Experiment Video
Updated: Aug 10, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Peripapillary choroidal neovascularization associated with melanocytoma of the optic disc: a clinicopathologic case
H Viet Tran1, Etienne H Bovey, Sylvie Uffer
1Jules Gonin University Eye Hospital, 15, Av. de France, 1004, Lausanne, VD, Switzerland.
Background:
Melanocytoma of the optic disc is a benign melanocytic tumor that rarely causes visual impairment. We report a case of a melanocytoma of the optic disc with a decreased vision related to a peripapillary choroidal neovascular membrane (PCNVM) that was successfully treated by submacular surgery.
Methods:
A 45-year-old southern European patient had a melanocytoma of the optic disc in his left eye with vision of 20/100. Fluorescein angiography demonstrated a PCNVM impeding the fovea associated with a subretinal hemorrhage.
Results:
The patient underwent a complete vitrectomy and removal of the PCNVM. Subsequently, the subretinal hemorrhage disappeared and visual acuity improved to 20/25. Visual acuity remained good for a period of 14 months' follow-up without any recurrence of neovascular membrane.
Conclusions:
Submacular surgery is a potentially effective treatment for large PCNVM associated with a melanocytoma of the optic disc.
