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Updated: Aug 10, 2026

09:03
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
Intracranial migration of silicone oil from an eye with optic pit
Ferenc Kuhn1, Ferenc Kover, Ilona Szabo
1Helen Keller Foundation for Research and Education, Birmingham, AL, USA. fkuhn@mindspring.com
Abstract
Background:
The origin of subretinal fluid in eyes with optic pit remains controversial.
Methods:
Case report.
Results:
The authors found that silicone oil, implanted into an eye that developed proliferative vitreoretinopathy after surgery for optic pit-related macular detachment, has migrated into the subarachnoid space.
Conclusions:
As this case shows, cerebrospinal fluid may migrate into the submacular space in eyes with optic pits.

