Monochromatic aberrations in eyes with different intraocular lens optic designs

To study the wavefront aberration profile of eyes with three different types of intraocular lenses (IOLs)--the Tecnis Z9000 (modified prolate surface design) (Pfizer, New York, NY), the Acrysof MA60BM (unequal biconvex optic) (Alcon, Ft Worth, Tex), and the Sensar Optiedge AR40e (equibiconvex optic) (AMO, Santa Ana, Calif)--in eyes following cataract surgery.

This study was conducted in two parts. The first part was a randomized open study of 32 eyes of 16 patients who underwent bilateral phacoemulsification with a foldable IOL in the capsular bag. A Tecnis Z9000 IOL was implanted in one eye and an Acrysof MA60BM IOL in the fellow eye. The ALLEGRETTO WAVE Analyzer (Wavelight Laser Technologies AG, Erlangen, Germany) was used to measure ocular aberrations 2 weeks after surgery. A paired t test was used to compare each Zernike term from Z3(-3) to Z6(6) between fellow eyes (pupil diameter = 6 mm). In the second part of the study, the wavefront aberrations of 16 eyes that underwent an identical surgical procedure as in the first part of the study but had a Sensar Optiedge AR40e IOL implanted were studied and compared with eyes with the Tecnis Z9000 and Acrysof MA60BM IOLs.

The mean spherical aberration (Z4(0)) was statistically significantly lower in eyes with a Tecnis Z9000 IOL (Z4(0) = 0.07 +/- 0.12 microm) compared with eyes with an Acrysof MA60BM IOL (Z4(0) = 0.29 +/- 0.20 microm, P < .001) and with eyes with a Sensar Optiedge AR40e IOL (Z4(0) = 0.20 +/- 0.09 microm, P = .002). No statistically significant differences were noted in any of the Zernike terms between eyes with Acrysof MA60BM and Sensar Optiedge AR40e IOLs, or in the root-mean-square (RMS) of total higher order aberrations among the three IOL groups.

The implantation of a Tecnis Z9000 IOL produces a significant reduction in spherical aberration of the eye. No significant differences were noted in the wavefront profile between eyes with Acrysof MA60BM and Sensar Optiedge AR40e IOLs. No significant differences were found in the RMS of total higher order aberrations among the three IOL groups.