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Updated: Aug 10, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
[Pediatric liver transplantation]
Gustavo Varela-Fascinetto1, Roberto Dávila-Pérez, Alejandro Hernández-Plata
1Departamento de Trasplantes, Hospital Infantil de México Federico Gómez, D F. varelafas@aol.com
Insights
Pediatric liver transplantation offers excellent outcomes for children, with survival rates of 85-90%. Innovations in surgical techniques and specialized care have made this life-saving procedure highly effective for young patients.
Area of Science:
- Pediatric Surgery
- Hepatology
- Transplantation Medicine
Background:
- Pediatric liver transplantation has become a standard, effective therapy for children.
- Survival rates have significantly improved, reaching 85-90% one-year patient survival.
- Patients experience an enhanced quality of life post-transplant.
Purpose of the Study:
- To review the advancements and special considerations in pediatric liver transplantation.
- To highlight surgical innovations and anesthetic, immunosuppressive, and postoperative care.
- To present a successful case series from the Hospital Infantil de México Federico Gómez.
Main Methods:
- Review of surgical innovations: reduced size, live donor, split, and auxiliary partial transplantation.
- Analysis of anesthetic, immunosuppressive, and postoperative care challenges in pediatric recipients.
- Presentation of a national leading case series, including firsts in live donor and simultaneous liver-kidney transplants.
Main Results:
- Pediatric liver transplantation achieves high patient survival rates (85-90% at one year).
- Surgical innovations have expanded the feasibility of transplantation for pediatric patients.
- The Hospital Infantil de México has a leading successful series, including complex procedures.
Conclusions:
- Pediatric liver transplantation is a highly successful and evolving field.
- Specialized approaches in surgery, anesthesia, and post-operative care are crucial for pediatric success.
- Continued innovation and experienced centers are vital for improving outcomes in pediatric liver transplantation.
Abstract:
Pediatric liver transplantation has evolved over the last two decades into an effective and widely accepted therapy for infants and children. Currently, these high-risk patients achieve 85 to 90% one-year patient survival and an excellent quality of life. This paper reviews the special features of the pediatric recipient, the surgical innovations developed to be able to offer them a transplant (reduced size, live donor, split, and auxiliary partial transplantation), the most significant issues in anesthetic, immunosuppressive and postoperative care in children, as well as a global picture of the results. Additionally, the experience of the Hospital Infantil de México Federico Gómez is presented, as the largest and most successful series of pediatric liver transplantation in the country, where the first successful live donor liver transplantation and the first simultaneous liver-kidney transplantation in a child were performed.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

