Related Experiment Video
Updated: Aug 10, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
[Does contemporary pharmacotherapy limit coercion in psychiatry? Preliminary results]
Ewelina Dobrzyńska1, Joanna Rymaszewska, Tomasz Pawłowski
1Katedra i Klinika Psychiatrii AM we Wroclawiu.
Aim:
The goal of the present study was to examine whether contemporary psychopharmacotherapy (atypic neuroleptics) can have an impact on the patient's compliance and limit coercion (involuntary admission to hospital, coercive measures).
Method:
71 adult inpatients with diagnoses of the schizophrenia spectrum (F20 group according to ICD-10) admitted to psychiatric hospital were observed. 41 of them were treated with atypic neuroleptics before hospitalization and 30 with typical ones. Data about their pharmacotherapy before hospitalization, compliance, history of disease and coercion used during hospitalization were gathered and analysed by means of chi square Pearson's and Mann-Whitney's tests.
Results:
There were no significant differences in non-compliance, the type of admission to hospital and frequency of coercion measures used during hospitalization between groups of patients receiving atypic and typical antipsychotics. However, the group with atypic neurolepitics was nearly significantly more adherent to therapy than the typical ones.
Conclusions:
Results of the study did not confirm the impact of atypic neuroleptics on compliance and coercion connected with admission to hospital. A long-term study with an increased number of patients is needed to confirm the results of this study.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Psychosis and Antipsychotic Drugs: Overview
Drug Abuse and Addiction: Pharmacological Phenomena
Psychodynamic Therapy
