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Related Experiment Videos

[Dysembryoplastic neuroepithelial tumor; a case report].

H Hasegawa1, S Bitoh, K Koshino

  • 1Department of Neurosurgery, Osaka Koseinenkin Hospital.

No Shinkei Geka. Neurological Surgery
|June 1, 1991
PubMed
Summary

Dysembryoplastic neuroepithelial tumors are rare glial tumors typically affecting young patients with complex partial seizures. Surgical removal offers a favorable prognosis, leading to seizure freedom.

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Area of Science:

  • Neuro-oncology
  • Neuropathology

Background:

  • Dysembryoplastic neuroepithelial tumor (DNT) is a newly recognized glial tumor entity.
  • DNTs commonly present in young individuals with intractable partial epilepsy.

Observation:

  • A 16-year-old male presented with a 5-year history of complex partial seizures.
  • CT revealed a non-enhancing, low-density lesion in the right temporal lobe, eroding the inner table of the skull.
  • MRI demonstrated typical low T1 and high T2 signal intensities.

Findings:

  • Surgical resection of the intracortical, multinodular tumor resulted in complete seizure remission.
  • Histopathology confirmed a DNT characterized by cellular nodules within a microcystic astrocytic component containing neurons.

Implications:

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  • DNTs are surgically treatable intracranial tumors with a positive prognosis.
  • Recognition of DNTs is crucial for the differential diagnosis of low-density intracranial lesions on CT scans.