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Updated: Jul 13, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Obstructive sleep apnea-hypopnea syndrome]
O Sardón Prado1, E González Pérez-Yarza, A Aldasoro Ruiz
1Unidad de Neumología, Servicio de Pediatría, Hospital Donostia, San Sebastián, Spain. osardon@chdo.osakidetza.net
Insights
Childhood obstructive sleep apnea-hypopnea syndrome (OSAHS) is common, affecting 74.5% of analyzed patients. Adenotonsillar hypertrophy is the primary cause, and respiratory polygraphy effectively diagnoses this condition.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Otorhinolaryngology
Context:
- Adenotonsillar hypertrophy is a frequent cause of upper airway obstruction in children.
- Clinical suspicion of sleep-disordered breathing necessitates accurate diagnostic methods.
- Understanding the prevalence and characteristics of childhood obstructive sleep apnea-hypopnea syndrome (OSAHS) is crucial for effective management.
Purpose:
- To determine the prevalence of obstructive sleep apnea-hypopnea syndrome (OSAHS) in a pediatric cohort.
- To identify the primary causes of OSAHS in children, focusing on adenotonsillar hypertrophy.
- To evaluate the diagnostic utility of respiratory polygraphy (RP) in childhood OSAHS.
Summary:
- A cohort of 400 children underwent respiratory polygraphy (RP) for suspected sleep-disordered breathing.
- Obstructive sleep apnea-hypopnea syndrome (OSAHS) was diagnosed in 74.5% of patients, with mild, moderate, and severe cases identified.
- Adenotonsillar hypertrophy was the most common finding (52.75%), correlating with OSAHS diagnosis. Significant differences were noted in oxygen saturation and apnea-hypopnea index (AHI/h).
Impact:
- Respiratory polygraphy (RP) is a valuable tool for diagnosing childhood OSAHS.
- Early diagnosis and intervention for OSAHS, often linked to adenotonsillar hypertrophy, can improve pediatric health outcomes.
- This study highlights the high incidence of OSAHS in children and underscores the importance of addressing underlying causes like adenotonsillar hypertrophy.
Abstract:
We analyzed a cohort of 400 patients referred from the otorhinolaryngology department (40.05 %), primary care (PC) (36.52 %), and the pediatric pulmonary unit (17.63 %). The children were referred for clinical suspicion of apneas in 191 (47.87 %), snoring and apneas in 101 (25 %), and snoring in 87 (21.80 %). Adenotonsillar hypertrophy was found in 211 patients (52.75 %), tonsillar hypertrophy in 87 (21.75 %), and adenoid hypertrophy in 73 (18.25 %). All patients underwent respiratory polygraphy (RP) during sleep. Obstructive sleep apnea-hypopnea syndrome (OSAHS) was diagnosed in 298 patients (74.5 %). OSAHS was mild in 96 patients (24 %), moderate in 148 (37 %), and severe in 54 (13.5 %). The results of RP expressed in means plus standard deviation were as follows: number of apneas 21.38 (24.47), number of hypopneas 19.81 (20.74), apnea-hypopnea index per hour (AHI/h) 5.29 (7.10), mean oxygen saturation 94.60 (11.80), minimal saturation 83.14 (13.45), number of snores 98.27 (254.55), and snoring index per hour 5.68 (6.5). Significant differences were found between oxygen saturation and AHI/h per hour. No differences were found among age, mean oxygen saturation, area of residence, reason for consulting, and AHI/h. Adenotonsillectomy was performed in 289 patients (72.25 %) of the initial cohort. In conclusion, OSAHS in childhood is frequent. RP during sleep aids diagnosis. The main cause of OSAHS in children is adenotonsillar hypertrophy.
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