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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Delayed metastatic renal carcinoma to prostate
Alejandro Rodriguez1, Loveleen Kang, Chris Politis
1Genitourinary Oncology Program, Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, Florida 33612-9497, USA. armbkdd@yahoo.com
Urology
|March 11, 2006
Summary
Metastasis of renal cell carcinoma to the prostate is rare, with only five reported cases. A delayed, solitary prostate metastasis from kidney cancer was observed, suggesting radical prostatectomy as a treatment option.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Renal cell carcinoma (RCC) is the most common type of kidney cancer.
- Metastasis indicates cancer spread from the primary site to other body parts.
- Prostate cancer is a common malignancy in men, distinct from kidney cancer.
Observation:
- This report details a rare case of renal cell carcinoma metastasizing to the prostate.
- The metastasis presented 9 years after the initial kidney cancer diagnosis, a delayed and solitary occurrence.
- This brings the total reported cases of RCC metastasis to the prostate to five.
Findings:
- Common presenting symptoms for prostate metastasis from RCC include hematuria and bladder outlet obstruction.
- One case was incidentally discovered during a prostate biopsy.
- The current case highlights a solitary, delayed metachronous metastasis.
Implications:
- Radical prostatectomy may be a viable treatment option for patients with isolated prostate metastasis from RCC.
- Increased awareness of this rare presentation is crucial for accurate diagnosis and management.
- Further research into the mechanisms and optimal treatment of such rare metastases is warranted.
