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Updated: Aug 10, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Measurement of cough
1National Heart and Lung Institute, Imperial College and Royal Brompton Hospital, Dovehouse Street, London SW3 6LY, UK. f.chung@imperial.ac.uk
Persistent cough assessment is crucial for treatment and understanding its mechanisms. New tools measure cough counts and quality of life, but intensity and reflex sensitivity require further study.
Area of Science:
- Pulmonology
- Clinical Measurement
- Respiratory Medicine
Background:
- Cough is a prevalent symptom, necessitating accurate assessment for effective clinical management and research.
- Current assessment methods include subjective patient scores, quality of life impact, and objective cough counts, but a comprehensive understanding is lacking.
Purpose of the Study:
- To review current methods for cough assessment, including subjective and objective measures.
- To highlight the need for standardized measures of cough intensity and its relationship to cough reflex sensitivity.
Main Methods:
- Review of existing literature on cough assessment tools and methodologies.
- Discussion of patient-reported outcomes, objective cough monitoring devices, and cough reflex testing (e.g., citric acid, capsaicin).
Main Results:
- Various tools exist to measure cough severity, quality of life impact, and cough counts.
- The relationship between objective cough counts and perceived severity remains unclear.
- Cough reflex sensitivity, measured via challenges like citric acid, offers insights but needs integration with other measures.
Conclusions:
- Standardized methods are needed to correlate cough counts, intensity, and reflex sensitivity for comprehensive cough assessment.
- Further research is required to understand the interrelationships between different cough measurement techniques.
- Accurate and multifaceted cough assessment is vital for advancing therapeutic interventions and understanding cough pathophysiology.
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05:43Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid
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06:22Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
Published on: September 19, 2025
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