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[Pulmonary mucormycosis in a multiple-trauma patient]
W Grandin1, T Dessieux, P Hounfodji
1Département d'Anesthésie-Réanimation Chirurgicale-Samu, Centre Hospitalier Régional et Universitaire de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France. Grandinws@aol.com
Annales Francaises D'Anesthesie Et De Reanimation
|March 15, 2006
Summary
A rare pulmonary Absidia infection occurred in a trauma patient without typical risk factors. Early bronchoscopy and combined medical-surgical treatment led to resolution.
Area of Science:
- Mycology
- Pulmonology
- Infectious Diseases
Background:
- Mucormycosis are opportunistic fungal infections.
- These infections typically affect immunocompromised individuals or those with specific risk factors like diabetes mellitus.
Observation:
- An 18-year-old male with severe thoracic trauma developed an Absidia infection in his contused lung.
- The patient did not exhibit common risk factors for mucormycosis.
Findings:
- Early diagnosis was achieved through bronchoscopy.
- Treatment involved high-dose amphotericin B lipid formulation, itraconazole, and surgery.
- The infection resolved after 18 months of treatment.
Implications:
- This case highlights that mucormycosis can occur in non-predisposed patients, particularly after severe trauma.
- Prompt diagnosis via bronchoscopy is crucial for effective management.
- A combination of antifungal therapy and surgical intervention can successfully treat pulmonary mucormycosis.
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