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[Pulmonary mucormycosis in a multiple-trauma patient]

W Grandin1, T Dessieux, P Hounfodji

  • 1Département d'Anesthésie-Réanimation Chirurgicale-Samu, Centre Hospitalier Régional et Universitaire de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France. Grandinws@aol.com

Annales Francaises D'Anesthesie Et De Reanimation
|March 15, 2006
PubMed

Insights

A rare pulmonary Absidia infection occurred in a trauma patient without typical risk factors. Early bronchoscopy and combined medical-surgical treatment led to resolution.

Area of Science:

  • Mycology
  • Pulmonology
  • Infectious Diseases

Background:

  • Mucormycosis are opportunistic fungal infections.
  • These infections typically affect immunocompromised individuals or those with specific risk factors like diabetes mellitus.

Observation:

  • An 18-year-old male with severe thoracic trauma developed an Absidia infection in his contused lung.
  • The patient did not exhibit common risk factors for mucormycosis.

Findings:

  • Early diagnosis was achieved through bronchoscopy.
  • Treatment involved high-dose amphotericin B lipid formulation, itraconazole, and surgery.
  • The infection resolved after 18 months of treatment.

Implications:

  • This case highlights that mucormycosis can occur in non-predisposed patients, particularly after severe trauma.
  • Prompt diagnosis via bronchoscopy is crucial for effective management.
  • A combination of antifungal therapy and surgical intervention can successfully treat pulmonary mucormycosis.

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