Related Experiment Video
Updated: Aug 10, 2026
Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Hematologic status in patients with recurrent aphthous stomatitis in Jordan
Samar Z Burgan1, Faleh A Sawair, Zouhair O Amarin
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Jordan, Amman, Jordan.
Objective:
To determine the prevalence of hematinic deficiencies in patients with recurrent aphthous stomatitis.
Methods:
The study took place in the Oral Medicine Clinic of the Jordan University Hospital in Amman, Jordan, between January 1993 and December 2000. We studied the hemoglobin, serum ferritin, vitamin B12 and folate levels in 143 patients with recurrent aphthous stomatitis. We compared the results with a control group of 143 age- and gender-matched patients with a range of other oral diseases.
Results:
In recurrent aphthous stomatitis patients, 14% were anemic and 37.8% showed hematinic deficiencies; 16.8% showed low serum ferritin; 26.6% showed low serum vitamin B12 and 4.9% showed low serum folate. In the control group, 10.5% were anemic and 18.2% showed hematinic deficiencies; 9.8% showed low serum ferritin; 12.6% showed low serum vitamin B12 and none showed serum folate deficiency.
Conclusion:
Patients with recurrent aphthous stomatitis have more hematinic deficiencies, particularly vitamin B12 deficiency, compared with controls. Correction of these hematinic deficiencies could help in the management of the disease.
Related Concept Videos
01:30Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
01:21Rheumatic Heart Disease III: Medical Management
01:25Endocarditis II: Clinical Features of Infective Endocarditis