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[Epidemiology of Haemophilus influenzae meningitis in Tunisia]
1C.H.U. de Monastir, Tunisie. mohamed.soltani@fmm.rnu.tn
Insights
Haemophilus influenzae type b (Hib) meningitis surveillance in Tunisia revealed a high incidence in young children. The study supported the cost-effectiveness of introducing Hib vaccination to prevent this serious infection.
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology
- Public Health Surveillance
Context:
- Haemophilus influenzae type b (Hib) meningitis poses a significant threat to children under 5 years old.
- Tunisia established a surveillance system to monitor meningitis cases and identify causative agents.
- The study period spanned 14 months, from June 2000, utilizing both population-based and sentinel surveillance methods.
Purpose:
- To determine the incidence of Haemophilus influenzae type b meningitis in children under 5 years in Tunisia.
- To analyze the microbiological causes of meningitis in the studied population.
- To evaluate the economic implications of Hib meningitis and compare it with the cost of vaccination.
Summary:
- A total of 80 meningitis cases were recorded, with Haemophilus influenzae isolated in 38% of cases.
- The confirmed incidence of Hib meningitis was 14.4 per 100,000 children under 5.
- Hib meningitis disproportionately affected infants under 1 year and boys.
Impact:
- The estimated cost of managing Hib meningitis exceeded the projected cost of introducing Hib vaccination.
- Based on these findings, the Tunisian Ministry of Health decided to implement Hib vaccination.
- This study provides crucial data supporting vaccine introduction for the prevention of Hib meningitis in Tunisia.
Abstract:
The incidence of Haemophilus influenzae b meningitis (Hib) in children < 5 years in Tunisia was studied through a surveillance system set up in June 2000 and followed for 14 months. Population-based surveillance began in 3 governorates and sentinel surveillance in 2. Children < 5 years suspected of meningitis had lumbar puncture, macroscopic exam, blood count, chemical analysis and culture carried out. In the 14 months, 80 cases of meningitis were recorded. From the population-based surveillance most cases were children < 1 year (73.6%) and boys (64%). H. influenzae was isolated in 38% of cases, pneumococci in 13% and meningococci in 7%. The incidence of confirmed Hib was 14.4/100 000 children. The estimated cost of identifying and treating Hib meningitis and its complications was greater than the cost of vaccine introduction. Based this study, the Ministry of Health has decided to introduce Hib vaccination.
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