Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Accurate two-dimensional IMRT verification using a back-projection EPID dosimetry method.

Markus Wendling1, Robert J W Louwe, Leah N McDermott

  • 1The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Department of Radiation Oncology, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Medical Physics
|March 15, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical feasibility of fast adaptive four-dimensional cone-beam computed tomography for lung cancer radiotherapy.

Physics and imaging in radiation oncology·2026
Same author

Simultaneous concurrent chemoradiation and SBRT in stage III NSCLC: Safety report of the phase I hybrid trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Estimation of accumulated dose to organs at risk in head and neck cancer patients treated with scheduled replanning and dose painting in the ARTFORCE trial.

Physics and imaging in radiation oncology·2026
Same author

Dose-based evaluation of delineation variation in radiotherapy: A scoping review.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Acute and long-term toxicity profiles and final oncologic outcomes in the phase III ARTFORCE trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Automated target misalignment correction for cone beam computed tomography-based online adaptive radiotherapy of locally advanced lung cancer patients.

Physics and imaging in radiation oncology·2025

This study presents a modified electronic portal imaging device (EPID) algorithm for accurate 2D dose reconstruction in intensity-modulated radiation therapy (IMRT). The validated EPID dosimetry method offers a reliable alternative to film for pretreatment IMRT verification.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Imaging Science

Background:

  • Electronic Portal Imaging Devices (EPIDs) are crucial for verifying radiation therapy doses.
  • Intensity-Modulated Radiation Therapy (IMRT) requires precise dosimetric verification.
  • Existing EPID algorithms needed modification for advanced IMRT techniques.

Purpose of the Study:

  • To modify and validate an EPID back-projection algorithm for IMRT dose reconstruction.
  • To assess the accuracy of the modified algorithm using amorphous silicon EPIDs.
  • To evaluate EPID dosimetry as a replacement for film-based verification in IMRT.

Main Methods:

  • Modified a previously developed EPID back-projection algorithm for IMRT.
  • Utilized an amorphous silicon EPID and ionization chamber measurements for model parametrization.

Related Experiment Videos

  • Reconstructed 2D dose distributions and compared them with film measurements using the y-evaluation method.

    • Main Results:

    • The modified algorithm accurately described lateral scatter within the EPID.
    • Back-projected 2D dose distributions showed high accuracy compared to reference data.
    • Excellent agreement was achieved between EPID and film measurements for prostate cancer IMRT plans.

    Conclusions:

    • The modified EPID algorithm accurately predicts dose distributions in homogeneous phantoms.
    • EPID dosimetry is a reliable and potentially fast tool for pretreatment IMRT verification.
    • EPID measurements can replace traditional film measurements for IMRT field verification.