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Sphincter of Oddi dysfunction in children
Moises Guelrud1, Leonel Rodriguez
1Advanced Endoscopic Therapy, Tufts-New England Medical Center, Tufts University Medical School, Boston, MA 02111, USA. mguelrud@tufts-nemc.org
Insights
Sphincter of Oddi dysfunction (SOD) is a rare motility disorder in children, often linked to pancreatitis. Endoscopic dual sphincterotomy is used, but its pediatric safety and effectiveness require more research.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
Background:
- Sphincter of Oddi dysfunction (SOD) is a rare condition affecting biliary and pancreatic sphincter motility.
- It is infrequently reported in children, primarily associated with idiopathic recurrent pancreatitis.
- Current treatment involves endoscopic dual sphincterotomy, but pediatric data is limited.
Purpose of the Study:
- To review the current understanding of Sphincter of Oddi dysfunction in the pediatric population.
- To highlight the treatment modalities and the need for further investigation into their safety and efficacy in children.
Main Methods:
- Literature review of pediatric cases with Sphincter of Oddi dysfunction.
- Analysis of treatment outcomes for endoscopic dual sphincterotomy in children.
Main Results:
- SOD in children is predominantly seen in those with idiopathic recurrent pancreatitis.
- Endoscopic dual sphincterotomy is the primary therapeutic approach.
- Limited data exists on the long-term safety and efficacy of these procedures in pediatric patients.
Conclusions:
- Sphincter of Oddi dysfunction is a rare but significant condition in pediatric patients, particularly those with recurrent pancreatitis.
- Further research is crucial to establish the safety and efficacy of manometry and sphincterotomy in children.
Abstract:
Sphincter of Oddi dysfunction (SOD) is a clinical entity caused by a primary motility alteration of either the biliary or the pancreatic sphincter. SOD is a rare condition that has been scarcely reported in children. Most of the reported literature has been in children with idiopathic recurrent pancreatitis. These children are treated endoscopically by dual sphincterotomy of the pancreatic and common duct sphincters. However, the safety and efficacy of sphincter of Oddi manometry and sphincterotomy in the pediatric population await further study.
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