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Isolated bone marrow occurrence of classic Hodgkin's lymphoma in an HIV-negative patient
Maurilio Ponzoni1, Fabio Ciceri, Roberto Crocchiolo
1Pathology Unit, Department of Oncology, San Raffaele H Scientific Institute, Milan, Italy. ponzoni.maurilio@hsr.it
Abstract:
Classic Hodgkin's Lymphoma is a disease usually characterized by lymph nodal presentation. Rare cases with extra-nodal first clinical manifestation may occur, and primary bone marrow involvement may be part of them: isolated bone marrow forms have been recently described in the context of HIV infection. We herein report a case of isolated bone marrow Hodgkin's Lymphoma occurrence in a HIV-negative, elderly patient. The impacts of such unusual Hodgkin's Lymphoma manifestation on clinical practice as well as the related diagnostic and therapeutic implications are discussed.
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