Related Experiment Video
Updated: Aug 10, 2026

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
Published on: June 13, 2025
Does the circadian pattern for acute cardiac events presentation vary with fasting?
J Al Suwaidi1, A Bener, A A Gehani
1Department of Cardiology and Cardiovascular Surgery, Doha, Qatar. jha01@hmc.org.qa
Ramadan fasting affects the timing of acute cardiac events. Changes in food and sleep patterns during fasting significantly alter the circadian rhythm, influencing when heart problems occur.
Area of Science:
- Cardiology
- Chronobiology
- Public Health
Background:
- Over one billion Muslims observe Ramadan fasting globally.
- The effect of Ramadan fasting on the circadian presentation of acute cardiac events remains largely unknown.
Purpose of the Study:
- To investigate the potential influence of Ramadan fasting on the timing of acute cardiac events.
- To determine if fasting alters the circadian patterns of cardiovascular events.
Main Methods:
- A prospective study was conducted in a general hospital setting.
- Patients with acute coronary events were categorized based on their fasting status.
- Statistical analyses, including Student's t-test, Mann-Whitney U-test, and chi2 analysis, were used to evaluate symptom presentation times.
Main Results:
- Out of 1019 patients, 162 were fasting during the study period.
- While some non-significant trends in emergency department presentation times were observed, fasting patients showed statistically significant differences in the timing of initial cardiac symptoms (P=0.002).
- Specifically, fasting patients were less likely to experience symptom onset between 5-8 AM and more likely between 5-6 PM or 3-4 AM.
Conclusions:
- Fasting during Ramadan, through alterations in food intake and sleep schedules, impacts the body's circadian rhythm.
- These circadian rhythm modifications influence the timing of acute coronary event symptom presentation.
Related Concept Videos
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Acute Coronary Syndrome III: Diagnostic Studies
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Circadian Rhythms and Gene Regulation
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
