Coronary surgery in patients requiring chronic hemodialysis

T Krabatsch1, R Yeter, R Hetzer

  • 1Deutsches Herzzentrum Berlin, Klinik fur Herz-, Thorax- und Gefasschirurgie, Berlin, Deutschland, Germany. krabatsch@dhzb.de

Insights

Coronary artery bypass grafting (CABG) in chronic dialysis patients has a 5.6% perioperative mortality. Mid-term survival is acceptable when tailored care is provided for this unique patient group.

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Critical Care Medicine

Background:

  • Coronary artery bypass grafting (CABG) in patients with chronic kidney disease on hemodialysis presents unique perioperative challenges.
  • Uremic patients often have comorbidities, including peripheral artery disease and anemia, complicating surgical management.

Purpose of the Study:

  • To evaluate the outcomes of CABG in patients requiring chronic hemodialysis.
  • To compare the results with a matched control group of non-uremic patients undergoing CABG.

Main Methods:

  • Retrospective analysis of 71 chronic dialysis patients who underwent CABG between 2001 and 2004.
  • Comparison with a randomized control group of 68 non-uremic patients who underwent CABG during the same period.

Main Results:

  • The incidence of CABG among chronic dialysis patients was 1.12% (71 out of 6315).
  • Perioperative mortality in the dialysis group was 5.6%.
  • One-year survival was 87.7% for uremic patients vs. 91.0% for controls; 4-year survival was 56.7% vs. 88.0%, respectively. Dialysis patients had higher rates of peripheral artery disease, lower hemoglobin, and required more transfusions.

Conclusions:

  • Coronary artery bypass grafting can be performed in uremic patients with acceptable mid-term survival rates.
  • Careful consideration of the specific needs of dialysis patients is crucial for successful perioperative management and improved outcomes.
Abstract

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...