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Updated: Aug 10, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Anaesthesia and sedation for gastrointestinal endoscopy
Kate Leslie1, Christopher A Stonell
1Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Parkville, Australia. kate.leslie@mh.org.au
Purpose Of Review:
Wide variations exist around the world in the practice of sedation for endoscopy, in terms of the depth of sedation, drug choices, delivery methods and the practitioners involved. These variations are driven by historical, cultural and economic factors. Professional bodies have promulgated guidelines in an attempt to unify and raise standards for sedation and monitoring. Nevertheless, preventable morbidity associated with sedation still occurs. A review of the recent literature is therefore justified.
Recent Findings:
The main themes in this literature are the advent of the widespread use of propofol by non-anaesthesiologists, and particularly non-medical staff; novel methods for administering propofol; the acceptability of endoscopy without sedation; and emerging technologies that obviate the need for endoscopy.
Summary:
There is still much scope to research and refine sedation techniques for endoscopy. We believe that the involvement of anaesthesiologists in this research is vital.
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