Related Experiment Video
Updated: Aug 10, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
Home blood pressure self-monitoring: diagnostic performance in white-coat hypertension
Joan Bayó1, Francesc Xavier Cos, Carme Roca
1PCT El Clot, ICS Consorci Sanitari Creu Roja d'Hospitalet, Faculty of Medicine, Biomedical Research Institute August Pi i Sunyer, University of Barcelona, Barcelona, Spain. 27515jbl@comb.es
Insights
A 3-day home blood pressure self-monitoring program showed poor diagnostic accuracy for white-coat hypertension. Ambulatory blood pressure monitoring remains the preferred diagnostic tool for this condition.
Area of Science:
- Cardiology
- Hypertension Management
- Diagnostic Accuracy
Background:
- White-coat hypertension (WCH) is a condition where blood pressure is elevated in a clinical setting but normal otherwise.
- Accurate diagnosis of WCH is crucial to avoid unnecessary treatment and its associated side effects.
Purpose of the Study:
- To evaluate the diagnostic performance of a 3-day home blood pressure self-monitoring (HBPSM) program for identifying white-coat hypertension.
- To compare HBPSM with 24-hour ambulatory blood pressure monitoring (ABPM) in diagnosing WCH.
Main Methods:
- A study involving 190 patients with newly diagnosed mild-moderate hypertension.
- Patients performed 3-day HBPSM (morning and night, triplicate readings).
- Comparison with 24-hour ABPM, using a normality cut-off of 135/85 mmHg for both methods.
Main Results:
- HBPSM diagnosed WCH in 34.8% of patients, while ABPM identified it in 41.6%.
- HBPSM demonstrated sensitivity of 50.0% and specificity of 75.7%.
- Receiver operating characteristic curve analysis did not improve HBPSM's diagnostic performance.
Conclusions:
- A 3-day HBPSM program exhibits poor diagnostic accuracy for white-coat hypertension.
- 24-hour ABPM remains the gold standard and recommended diagnostic test for WCH.
Objective:
To determine the diagnostic performance of home blood pressure self-monitoring in white-coat hypertension using a 3-day reading program.
Material And Methods:
One hundred and ninety nontreated patients recently diagnosed with mild-moderate hypertension, selected consecutively at four primary healthcare centers in the city of Barcelona, were included. Each patient underwent morning and night home blood pressure self-monitoring with readings in triplicate for three consecutive days, followed by 24-h ambulatory blood pressure monitoring. The normality cut-off point value for home blood pressure self-monitoring and daytime ambulatory blood pressure monitoring was 135/85 mmHg.
Results:
Sixty-three patients were diagnosed with white-coat hypertension with home blood pressure self-monitoring (34.8%; 95% confidence interval: 27.9-42.2) and 74 with ambulatory blood pressure monitoring (41.6%; 95% confidence interval: 33.7-48.4). No statistically significant differences were observed between home blood pressure self-monitoring values and those of diurnal ambulatory blood pressure monitoring [137.4 (14.3)/82.1 (8.3) mmHg vs. 134.8 (11.3)/81.3 (9.5) mmHg]. Home blood pressure self-monitoring diagnostic performance parameters were sensitivity 50.0% (95% confidence interval: 38.3-61.7), specificity 75.7% (95% confidence interval: 66.3-83.2), positive and negative predictive values 58.7% (95% confidence interval: 45.6-70.8) and 68.6% (95% confidence interval: 59.4-76.7), respectively, and positive and negative probability coefficients 2.05 and 0.66, respectively. Analysis of different normality cut-off points using a receiver operating characteristic curve failed to produce significant improvement in the diagnostic performance of home blood pressure self-monitoring.
Conclusions:
The diagnostic accuracy of a 3-day home blood pressure self-monitoring reading program in white-coat hypertension was poor. Ambulatory blood pressure monitoring continues to be the test of choice for this indication.
Related Concept Videos
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Hypertension III: Clinical Manifestations and Diagnostic Studies
Errors occurring during blood pressure monitoring
Several factors...
Pre-Procedural Guidelines for Assessing Blood Pressure
Assessment of blood pressure in brachial artery(two-step method)
Measurement of Blood Pressure