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Virus Propagation and Cell-Based Colorimetric Quantification
Published on: April 7, 2023
Disinfecting solutions for soft contact lenses using different color indicators
Rosa M García-Monlleó1, Maria J Rivas, Rafael Huertas
1Departamento de Optica, Facultad de Ciencia, Universidad de Granada, Granada, Spain.
Summary
New color indicators in soft contact lens disinfecting solutions provide a safe and useful visual tool for users. These new hydrogen peroxide systems show improved color changes and effectiveness compared to older solutions.
Area of Science:
- Ophthalmology and Materials Science
- Focus on contact lens care and disinfection technologies.
Background:
- Soft contact lens disinfection commonly utilizes hydrogen peroxide systems.
- Accurate monitoring of disinfection efficacy is crucial for eye health.
- Existing color indicators may have limitations in clarity or user-friendliness.
Purpose of the Study:
- To analyze color changes in two commercial soft contact lens disinfecting solutions with new color indicators.
- To examine the relationship between temporal color evolution and hydrogen peroxide concentration.
- To compare these new solutions with a commercial solution using a different color indicator.
Main Methods:
- Color measurements of disinfecting solutions were taken at 2-minute intervals for over 2 hours using a spectroradiometer.
- Hydrogen peroxide concentration was measured using a spectrophotometer.
- Standard indoor and outdoor light sources were employed during color analysis.
Main Results:
- The two new disinfecting solutions exhibited qualitatively different temporal color evolutions.
- Induced CIELAB color differences were significantly greater (1.5x and 2.2x) than the comparative solution.
- New solutions showed color changes closer to the tritan confusion line, beneficial for color vision deficiency.
- After 2 hours, hydrogen peroxide concentration was approximately one-third of the earlier solution.
- Statistically significant correlations (p < 0.01) were found between color change and hydrogen peroxide concentration (r = -0.878 and r = -0.990).
Conclusions:
- Color changes in hydrogen peroxide disinfection systems serve as a safe and effective visual indicator for contact lens wearers.
- The analyzed new disinfecting solutions offer significant improvements over the previous generation.
- Enhanced visual cues and improved disinfection monitoring are key benefits.
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