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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
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Hypermetropia-succeeded myopia after hyperbaric oxygen therapy.

Knut Evanger1, Olav H Haugen, Leif Aanderud

  • 1Department of Hyperbaric Medicine, Haukeland University Hospital, Haukeland, Norway. knut.evanger@essilor.no

Optometry and Vision Science : Official Publication of the American Academy of Optometry
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PubMed
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Hyperbaric oxygen therapy can cause temporary vision changes, including shifts in refractive error. This case study details a patient experiencing myopic and hypermetropic shifts during treatment, with eventual stabilization.

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Area of Science:

  • Ophthalmology
  • Hyperbaric Medicine
  • Physiological Optics

Background:

  • Hyperbaric oxygen (HBO) therapy is used for various medical conditions.
  • Changes in visual function have been anecdotally reported during HBO treatment.
  • Understanding refractive changes associated with HBO is crucial for patient management.

Observation:

  • A 58-year-old male patient undergoing HBO therapy reported altered vision.
  • The patient experienced sequential myopic and then hypermetropic shifts in both eyes.
  • These refractive changes occurred after each of two HBO treatment series.

Findings:

  • The patient exhibited a maximal refractive amplitude of 3.00 D in the right eye and 2.75 D in the left eye.
  • Refractive errors ranged from -1.37 D to +1.62 D (right eye) and -1.25 D to +1.50 D (left eye).
  • Visual refraction stabilized approximately 1.5 years post-treatment, returning to near pre-treatment levels.

Implications:

  • The observed refractive shifts may be linked to structural alterations within the eye's lens.
  • HBO therapy can induce transient refractive changes, necessitating careful ophthalmological monitoring.
  • Further research is needed to elucidate the precise mechanisms of HBO-induced visual changes.