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Related Experiment Videos

[Eosinophilia and hepatopathy].

R Fatio1, A Häne, U Hürlimann

  • 1Klinik für Innere Medizin, Spital Zollikerberg.

Praxis
|March 16, 2006
PubMed
Summary
This summary is machine-generated.

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A 70-year-old patient with severe eosinophilia and abdominal pain was initially treated for idiopathic hypereosinophilic syndrome. Subsequent diagnosis and treatment of strongyloidiasis resolved the condition, highlighting the importance of considering parasitic infections in unexplained eosinophilia.

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Gastroenterology

Background:

  • Eosinophilia can indicate allergic, infectious, or neoplastic conditions, ranging from mild to life-threatening.
  • Idiopathic hypereosinophilic syndrome (HES) is a diagnosis of exclusion characterized by persistent eosinophilia.
  • Strongyloides infection is a parasitic disease that can remain asymptomatic for years.

Observation:

  • A 70-year-old patient presented with diffuse abdominal pain, severe eosinophilia, and elevated liver parameters.
  • Initial treatment for presumed HES with high-dose methylprednisolone led to rapid normalization of eosinophil counts and liver enzymes.
  • Further investigation revealed a positive ELISA test for strongyloidiasis.

Findings:

  • Strongyloidiasis was identified as the underlying cause of the patient's severe eosinophilia and symptoms.

Related Experiment Videos

  • Treatment with mebendazole resulted in successful resolution of the parasitic infection.
  • The case underscores the potential for strongyloidiasis to mimic other causes of eosinophilia.

    • Implications:

    • Parasitic infections, particularly strongyloidiasis, should be considered in the differential diagnosis of unexplained eosinophilia, even in the absence of typical symptoms.
    • Accurate diagnosis and targeted antiparasitic treatment are crucial for managing eosinophilia secondary to infections.
    • This case highlights the importance of a comprehensive diagnostic approach in patients with persistent eosinophilia and gastrointestinal symptoms.