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Vaginal rhabdomyosarcoma in a dog
K Suzuki1, K Nakatani, H Shibuya
1College of Bioresource Sciences, Nihon University, Department of Veterinary Pathology, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan. kazuhiko@brs.nihon-u.ac.jp
Veterinary Pathology
|March 16, 2006
Summary
A rare botryoid rhabdomyosarcoma, a type of soft tissue cancer, was diagnosed in a dog
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Soft Tissue Sarcomas
Background:
- Rhabdomyosarcoma is a malignant tumor arising from skeletal muscle cells.
- The botryoid subtype is characterized by a grape-like cluster appearance, often found in hollow organs.
- This subtype is rare in domestic animals, with limited case reports.
Observation:
- A 10-year-old female dog presented with vulvar hemorrhage.
- Magnetic resonance imaging (MRI) and endoscopy revealed a multipapillary, grape-like mass near the urethral opening.
- Histopathology showed poorly differentiated tumor cells with multinuclear cells and frequent mitoses.
Findings:
- Immunohistochemistry confirmed tumor cells positive for vimentin and focally for desmin, but negative for myoglobin.
- The findings supported a diagnosis of poorly differentiated botryoid rhabdomyosarcoma.
- This represents the first documented case of vaginal botryoid rhabdomyosarcoma in a dog.
Implications:
- This case expands the understanding of rhabdomyosarcoma presentation in veterinary medicine.
- Highlights the importance of advanced imaging and immunohistochemistry in diagnosing rare canine tumors.
- Contributes to the limited literature on botryoid rhabdomyosarcoma in dogs, aiding future research and clinical management.
