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Updated: Aug 10, 2026

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
Published on: May 21, 2015
[Applied DNA-DNA hybridization in determination of oral Streptococcus.]
1School of Stomatology, Shanghai Second Medical University. Shanghai 200011,China.
Abstract:
Quantitative measurement of DNA-DNA hybridization is a new technique for determination of unknown bacteria.It is more valuable how to identify strains which is rare difference on phenotypic characteristics.It is important to resolve bactericial taxionmy and identify new strain.Four strain of Streptiococcus are determined by hybridization of DNA.Some technique problems are discussed.Such as purification,precision of DNA and temperature as well as time of DNA hybridization and standard of judgment.
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