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Updated: Aug 10, 2026

Basic Surgical Techniques in the Göttingen Minipig: Intubation, Bladder Catheterization, Femoral Vessel Catheterization, and Transcardial Perfusion
Published on: June 26, 2011
Surgical technique for long-term cecal cannulation in the Yucatan minipig (Sus scrofa domestica)
Diana L Eubanks1, Robert Cooper, J Gregg Boring
1Biomedical Research Center, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA. deubanks@cvm.msstate.edu
Abstract:
Measurements of standardized ileal digestibility yield more useful results than do those of fecal digestibility. To that end, cecal cannulation of the pig has been performed extensively in an attempt to model the digestive processes of humans. Here we introduce a technique for the placement of a permanent cecal cannula with a silicon port that is larger in diameter than those previously described in the literature. A large lumen offers several advantages, most notably ease in collection of larger samples and introduction of materials into the cecum. To date, this technique has been used successfully to cannulate 39 Yucatan minipigs at our institution. Long-term, there have been no major complications with the procedure or cannulas.
