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Updated: Aug 10, 2026
Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
Published on: December 16, 2017
[Pancreatic transplantation. Results of the Málaga group]
Alfonso Navarro-Piñero1, M Jesús Castro-Santiago, José Manuel Aranda-Narváez
1Servicio de Cirugía General, Digestiva y Trasplante de Organos Sólidos Abdominales, Hospital Regional Universitario Carlos Haya, Málaga, Spain. alfonso.navarro.sspa@juntadeandalucia.es
Introduction:
Pancreatic transplantation is currently the only therapeutic alternative able to restore normal blood glucose levels in diabetic patients. Moreover, this procedure can halt or even reverse diabetes-related complications. The aim of this study was to present our experience and the results of the first 4 years of a pancreatic transplantation program in our center.
Material And Method:
From February 2000 to June 2004, 43 pancreatic transplantations were performed in 42 recipients in the Carlos Haya Regional Hospital in Malaga (Spain). In all patients, the technique of enteric drainage of exocrine pancreatic secretions and systemic venous shunting of endocrine secretions (to the inferior vena cava) was used.
Results:
There were 37 (88.1%) simultaneous pancreas-kidney transplantations, 4 (9.5%) in patients with prior kidney transplantation and 1 retransplantation (2.4%). In all patients, glycosylated hemoglobin and C-peptide levels returned to normal. Patient and pancreatic graft survival were 91% and 84%, respectively, with a median follow-up of 19 months. The reintervation rate was 31%, with an overall rate of graft loss of 16%.
Conclusions:
The results obtained in our series are similar to those reported for large series.
