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Updated: Aug 10, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[Evolution of severe mitral regurgitation after optimization of pharmacological therapy in non-ischemic dilated
Domingo A Pascual Figal1, Gonzalo de la Morena Valenzuela, Josefa González Carrillo
1Servicio de Cardiología, Hospital Universitario Virgen de la Arrixaca, Murcia, España. dapascual@servicam.com
Abstract:
In dilated cardiomyopathy, severe functional mitral regurgitation (MR) is associated with a poor prognosis. In 112 consecutive clinically stable patients with non-ischemic dilated cardiomyopathy, echocardiography identified 15 (14%) patients who had severe MR (age, 53+/-12 years; 80% male; left ventricular ejection fraction, 26 +/- 8%). Existing medical treatment with ACE inhibitors and beta-blockers was increased up to the maximum tolerated doses. At 6 months, MR decreased by at least one grade in 13 (87%) patients (P =.001), as did the effective regurgitant orifice area (from 0.41 [0.05] mm2 to 0.20 [0.15] mm2; P.
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