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Updated: Aug 10, 2026

Cerebellar Regional Dissection for Molecular Analysis
Published on: December 5, 2020
Clinical insights into paraneoplastic cerebellar degeneration
1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. scheid@cbs.mpg.de
Abstract:
Neuroimaging is usually unremarkable in paraneoplastic cerebellar degeneration (PCD), at least in the early stages of the disease. A patient with proven PCD is reported in whom it could be shown that cerebellar atrophy evolved very rapidly and was present in early imaging studies. Even with the use of the whole spectrum of modern diagnostic tools, the underlying malignancy can be difficult to diagnose. In addition to mammography, MRI is recommended in these cases and repeat FDG-PET may be necessary.
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