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[Variations in hemostasis in the infant under deep hypothermia]
Annales De L'Anesthesiologie Francaise
|January 1, 1977
Summary
Deep hypothermia in infant heart surgery significantly impacts hemostasis. Coagulation factors decrease, fibrinolysis increases, and heparin levels vary unpredictably, necessitating protamine neutralization.
Area of Science:
- Pediatric Cardiology
- Hemostasis and Thrombosis
- Cardiovascular Surgery
Context:
- Deep hypothermia is employed in infant cardiac surgeries.
- Hemostatic balance is critical during these procedures.
Purpose:
- To investigate the hemostatic effects of deep hypothermia in infants undergoing cardiopathy surgery.
- To analyze changes in coagulation factors, fibrinolytic activity, and heparin neutralization.
Summary:
- Studied 29 infants undergoing deep hypothermic cardiopathy surgery.
- Observed decreased coagulation factor levels and increased fibrinolytic activity.
- Noted unpredictable residual heparin requiring protamine neutralization.
Impact:
- Highlights the complex hemostatic alterations during infant deep hypothermia.
- Informs clinical management strategies for hemostasis in pediatric cardiac surgery.
- Underscores the need for careful heparin management and monitoring.