Protein engineering of formate dehydrogenase

Vladimir I Tishkov1, Vladimir O Popov

  • 1Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Moscow 119992, Russia. vit@enz.chem.msu.ru

Summary

Enzyme engineering improves formate dehydrogenase (FDH) for NADH regeneration in chiral compound synthesis. Modifications enhance stability and reduce costs, enabling wider industrial application of this biocatalyst.

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