[Changes in various indicators of homeostasis after operation on the abdominal aorta in relation to the method of...

The influence of the method of anesthesia on the degree of changes of homeostasis after reconstructive operations on the abdominal aorta was studied in 95 patients. Under conditions of artificial ventilation of lungs fluothane narcosis was used in 9 patients, either narcosis--in 15 patients, combined neuroleptanalgesia--in 35 patients, epidural anesthesia with spontaneous respiration with atmospheric air--in 36 patients. It was shown that fluothane narcosis and neuroleptanalgesia brought about considerable changes of homeostasis and was followed by reliably greater amount of complications and lethal issues. A conclusion was made that general anesthetics, hyperoxia and artificial ventilation of lungs aggravate postischemic tissue alterations, inhibit hemopoiesis and functions of parenchymatous organs and provoke severe postoperative complications and lethal issues.