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Related Experiment Videos

Optimal perioperative oxygen administration.

Barbara Kabon1, Andrea Kurz

  • 1Department of Anesthesiology and General Intensive Care, Vienna General Hospital, University of Vienna, Austria.

Current Opinion in Anaesthesiology
|March 21, 2006
PubMed
Summary
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Perioperative supplemental oxygen improves immune function and reduces wound infections. This simple treatment may enhance patient outcomes without significant side effects, though optimal concentrations require further study.

Area of Science:

  • Anesthesiology
  • Surgical Care
  • Critical Care Medicine

Background:

  • Oxygen is routinely administered during anesthesia and surgery, with varying inspired concentrations.
  • Recent trials suggest perioperative supplemental oxygen may improve outcomes in specific surgical contexts.

Purpose of the Study:

  • To review the benefits and risks of supplemental oxygen administration in the perioperative period.
  • To provide an evidence-based overview for clinicians regarding perioperative oxygen therapy.

Main Methods:

  • Systematic review of randomized trials and existing literature.
  • Analysis of studies investigating the impact of supplemental oxygen on patient outcomes.

Main Results:

  • Supplemental oxygen enhances immune function and nearly doubles subcutaneous tissue oxygen tension.

Related Experiment Videos

  • An 80% inspired oxygen fraction halves postoperative wound infection rates and may reduce nausea and vomiting.
  • No clinically significant side effects were associated with supplemental perioperative oxygen administration.

    • Conclusions:

    • Perioperative supplemental oxygen is a potentially simple, inexpensive, and well-tolerated option to improve patient outcomes.
    • Further research is needed to determine the optimal inspired oxygen concentration for perioperative use.