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Updated: Aug 9, 2026
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A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
Published on: July 16, 2020
Endoscopy guided by an intraoperative 3D ultrasound-based neuronavigation system
O M Rygh1, J Cappelen, T Selbekk
1Department of Neurosurgery, St. Olav University Hospital, Trondheim, Norway. ola.rygh@ntnu.no
Minimally Invasive Neurosurgery : MIN
|March 21, 2006
Summary
3D ultrasound neuronavigation is feasible for guiding neuroendoscopy, offering sufficient image quality for planning and visualization. This technology aids in accurate procedures and can adapt to brain shift with updated imaging.
Area of Science:
- Neurosurgery
- Medical Imaging
- Surgical Navigation
Background:
- Neuroendoscopy requires precise guidance for minimally invasive procedures.
- Traditional neuronavigation systems may have limitations in real-time intraoperative adjustments.
Observation:
- A neuronavigation system integrated with 3D ultrasound was utilized for intraoperative guidance.
- 3D ultrasound and ultrasound angiography data were acquired during neurosurgical operations.
Findings:
- 3D ultrasound provided sufficient image quality for guiding neuroendoscopy, enabling accurate planning of entry points and trajectories.
- Ultrasound angiography successfully visualized critical blood vessels, including the basilar artery during a third ventriculostomy.
- Acquisition of updated 3D ultrasound datasets was rapid and facilitated adjustments for brain shift, with demonstrated cyst size reduction in some cases.
Implications:
- 3D ultrasound-based neuronavigation offers a viable tool for enhancing the accuracy and safety of neuroendoscopic procedures.
- The ability to acquire updated images and visualize vasculature in real-time has significant potential for improving surgical outcomes.
- This technology may help mitigate complications associated with brain shift during complex intracranial surgeries.
