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Updated: Aug 9, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
[Diagnosis of Takayasu's arteritis affecting carotid arteries with multi-slice spiral CT]
Wei Liu1, Hua-dan Xue, Zheng-yu Jin
1Department of Radiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Objective:
To explore changes in the carotid arteries in Tarkayasu arteritis (TA) with computed tomographic angiography (CTA).
Methods:
The common carotid artery intima-medial thickness (CCA-IMT) in 20 common carotid arteries (CCAs) in 10 controls and 40 CCAs in 20 patients with TA were analyzed and compared.
Results:
Contrast-enhanced CT scanning combined with the application of 3D reconstruction clearly showed the carotid vascular luminal abnormalities, such as stenosis, occlusion, dilation, and aneurysm formation. CCA-IMT increased in all the patients with TA affecting carotid arteries. CCA-IMT was significantly larger in the patients than in controls [(0.36 +/- 0.13) cm vs. (0.03 +/- 0.02) cm, P < 0.05] , and was significantly larger in patients with active diseases than in those without active diseases [(0.44 +/- 0.09) cm vs. (0.24 +/- 0.10) cm, P < 0.05].
Conclusion:
CCA-IMT increases in TA affecting carotid arteries, especially in active diseases.
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