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Updated: Aug 9, 2026

Modified In Vivo Matrix Gel Plug Assay for Angiogenesis Studies
Published on: June 30, 2023
[Angiogenesis--a novel therapeutic strategy for cardiovascular diseases]
Pei-li Wang1, Yan Lei, Ke-ji Chen
1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091. wpl0721@sohu.com
Abstract:
Angiogenesis is a biological process of growing new vessels from the existed vascular structure. Many factors, such as vascular endothelia growth factor and fibroblast growth factor, can stimulate the formation of new vessels. Promoting revascularization in ischemic myocardium has been a novel therapeutic strategy for ischemic cardiovascular diseases. Recently, investigators have done a lot of work in experimental researches and clinical trials, and made some progress. Nevertheless, there are still some problems to be solved in therapeutic angiogenesis. Clinical validity of traditional Chinese medicinal treatment and its therapeutic principles including strengthening qi and activating blood, removing blood stasis to stimulate generation of blood, etc. are the theoretic and clinical basis for TCM study on angiogenesis.
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