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[Is the sickle-cell trait a risk factor?].

Edmond Bertrand1

  • 1Agrégé du Service de santé des armées, Doyen honoraire de la Faculté de médecine d'Abidjan.

Medecine Tropicale : Revue Du Corps De Sante Colonial
|March 22, 2006
PubMed
Summary

Sickle-cell trait is generally safe but can pose risks like sudden death during strenuous activity or at high altitudes. A medical follow-up program and registry are proposed for at-risk individuals.

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Area of Science:

  • Hematology
  • Sports Medicine
  • Public Health

Context:

  • Sickle-cell trait is often considered benign, with few occupational restrictions.
  • However, case reports link it to serious events like visceral infarction and sudden death.

Purpose:

  • To highlight potential risks associated with sickle-cell trait.
  • To propose enhanced monitoring for athletes and military personnel.
  • To advocate for a national sudden death registry.

Summary:

  • While generally not a risk factor, sickle-cell trait can be associated with serious complications.
  • Factors such as high altitude, intense physical exertion, dehydration, and fever can elevate risk.
  • Medical surveillance and a national registry are suggested for early detection and data collection.

Impact:

  • Increased awareness of sickle-cell trait risks in specific populations.
  • Potential implementation of targeted medical follow-up programs.
  • Improved data collection on sudden deaths in athletes and military personnel.

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