Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A smoking cessation intervention for the methadone-maintained.

Michael D Stein1, Marjorie C Weinstock, Debra S Herman

  • 1Rhode Island Hospital, Division of General Internal Medicine, Brown University Medical School, Providence, RI 02903, USA. mstein@lifespan.org

Addiction (Abingdon, England)
|March 22, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HIV-related Stigma and Alcohol Involvement Among People with HIV Who Engage in Unhealthy Drinking.

AIDS and behavior·2026
Same author

DUI Detection From Gait Using a Multichannel 1DCNN-Attention-BiLSTM Framework.

IEEE access : practical innovations, open solutions·2025
Same author

Discriminating Between Marijuana and Alcohol Gait Impairments Using Tile CNN With TICA Pooling.

IEEE open journal of engineering in medicine and biology·2025
Same author

Identification of Opioid Medications Among Persons With Opioid Use Disorder and Chronic Pain.

Substance use & addiction journal·2025
Same author

Health Care Service Utilization Among People with HIV, Chronic Pain, and Depression: Utilization and Cost Outcomes from the HIV-PASS Study.

AIDS and behavior·2024
Same author

Associations of discomfort intolerance, discomfort avoidance, and cannabis and alcohol use among persons with chronic pain receiving prescription buprenorphine for opioid use disorder.

Drug and alcohol dependence·2024
Same journal

Cannabis use, affect and emotion regulation in daily life: A 3-week experience sampling method study in people who smoke cannabis almost daily.

Addiction (Abingdon, England)·2026
Same journal

Early trends in outpatient addiction care for cannabis use disorder following cannabis legalization in Germany: Evidence from National Monitoring Data.

Addiction (Abingdon, England)·2026
Same journal

Zyn and other oral nicotine pouch use, correlates, and advertising exposure among a national sample of United States adolescents, young adults and adults.

Addiction (Abingdon, England)·2026
Same journal

Trends in new psychoactive substance poisonings in the Netherlands: A 14-year retrospective analysis (2012-2025).

Addiction (Abingdon, England)·2026
Same journal

Theorizing ahead of the data: A commentary on Piper et al.

Addiction (Abingdon, England)·2026
Same journal

Longitudinal association of switching to dual cigarette and e-cigarette use vs. continued exclusive cigarette smoking with tobacco-specific nitrosamine and nicotine intake.

Addiction (Abingdon, England)·2026
See all related articles

A tailored behavioral intervention combined with a nicotine patch did not significantly increase smoking cessation rates in methadone-maintained smokers. Men showed higher success rates in quitting smoking.

Area of Science:

  • Addiction Medicine
  • Behavioral Psychology
  • Public Health

Background:

  • Smoking is a significant public health issue, particularly among individuals undergoing methadone maintenance treatment.
  • Nicotine replacement therapy and behavioral interventions are established methods for smoking cessation.

Purpose of the Study:

  • To evaluate the incremental efficacy of a maximal, tailored behavioral treatment compared to a minimal treatment, when both are combined with a nicotine patch, for smoking cessation in methadone-maintained smokers.

Main Methods:

  • A randomized clinical trial with a 6-month follow-up was conducted across five methadone maintenance treatment centers.
  • 383 methadone-maintained smokers were randomized to receive nicotine patch plus either maximal (tailored behavioral intervention) or minimal (brief advice) treatment.

Related Experiment Videos

  • Carbon monoxide-confirmed 7-day point smoking cessation prevalence at 3 and 6 months was the primary outcome measure.

    • Main Results:

    • At 6 months, the 7-day point prevalence of smoking cessation was 5.2% in the maximal treatment group and 4.7% in the minimal treatment group (P=0.81).
    • Logistic regression analysis indicated that males were significantly more likely to be abstinent at both 3 and 6 months.
    • No significant difference in quit rates was observed between the maximal and minimal behavioral intervention groups.

    Conclusions:

    • A tailored behavioral intervention, in addition to a nicotine patch and minimal treatment, did not improve smoking cessation rates in this population.
    • Smoking cessation rates remain low among methadone-maintained smokers.
    • Men demonstrated a higher likelihood of successful smoking cessation compared to women in this study.