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Renal transplantation in children
H Sözen1, A Dalgic, H Karakayali
1Department of General Surgery, Baskent University Hospital, Ankara, Turkey.
Transplantation Proceedings
|March 22, 2006
Summary
Pediatric kidney transplant recipients face unique challenges. Strict surgical techniques, improved immunosuppression, and prompt complication management can enhance outcomes for children undergoing renal transplantation.
Area of Science:
- Pediatric Nephrology
- Transplantation Surgery
- Immunology
Background:
- Pediatric kidney transplant recipients present unique immunological, metabolic, and technical considerations compared to adults.
- Children undergoing renal transplantation have a higher potential for post-transplant complications.
- This study retrospectively analyzed 83 pediatric kidney transplant cases.
Purpose of the Study:
- To evaluate the outcomes and complications of kidney transplantation in pediatric recipients.
- To identify factors influencing graft and patient survival in children.
Main Methods:
- Retrospective analysis of 83 pediatric patients (ages 7-17) who received kidney transplants between 1975 and 2004.
- Data collected included patient demographics, surgical procedures, morbidities, and survival rates.
- Comparison of outcomes between living related and cadaveric transplantations.
Main Results:
- 16.3% of recipients experienced morbidities, including lymphocele (8.1%) and graft renal artery stenosis (2.3%).
- Patient survival rates at 1, 3, and 5 years were high (98%, 93%, 92%).
- Graft survival rates at 1, 3, and 5 years were 91%, 78%, and 67% for living related and 92%, 76%, and 65% for cadaveric transplants, respectively.
Conclusions:
- Optimal outcomes in pediatric renal transplantation necessitate meticulous surgical techniques.
- Effective immunosuppressive strategies and early management of complications are crucial.
- Adherence to these principles can improve long-term graft and patient survival in pediatric recipients.