Related Experiment Video

Updated: Aug 9, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
05:06

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review

Published on: March 27, 2026

Venous thromboembolism after severe injury in children

Claude Cyr1, Bruno Michon, Géraldine Pettersen

  • 1Département de Pédiatrie, Faculté de Médecine, Université de Sherbrooke, Canada. claude.cyr@usherbrooke.ca

Acta Haematologica
|March 22, 2006
PubMed

Insights

Pediatric trauma patients with high Injury Severity Scores, thoracic or spinal injuries, or venous catheters face an increased risk of venous thromboembolism (VTE). Identifying these high-risk children is crucial for targeted VTE management strategies.

Area of Science:

  • Pediatric critical care medicine
  • Trauma surgery
  • Hematology

Background:

  • Deep vein thrombosis (DVT) and pulmonary embolism (PE) are common after major trauma.
  • Risk factors and incidence of VTE in injured children are not well-established.

Purpose of the Study:

  • To identify the incidence and risk factors for venous thromboembolism (VTE) in severely injured children.

Main Methods:

  • Retrospective review of severely injured children (<18 years) diagnosed with VTE between 1999 and 2002.
  • Multivariate analysis was used to identify independent risk factors for VTE.

Main Results:

  • VTE occurred in 3.3/1,000 pediatric trauma admissions.
  • Independent risk factors for VTE included older age, higher Injury Severity Scores, thoracic injuries, spinal injuries, and central venous catheters.

Conclusions:

  • Older children with severe injuries, specific injury types (thoracic, spinal), and venous catheters are at significant risk for VTE.
  • Identifying high-risk pediatric subgroups is essential for studying VTE prophylaxis, screening, and treatment strategies.
Abstract

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...