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Herpetic lesion mimicking lower eyelid malignancy
Julie M Sturm1, Mark R Levine, Amarpreet Singh
1Department of Ophthalmology, University Hospitals of Cleveland, Case Western Reserve, Cleveland, Ohio 44121, USA.
Ophthalmic Plastic and Reconstructive Surgery
|March 22, 2006
Summary
A rapidly growing eyelid lesion in an HIV-positive man was initially suspected to be malignant. Biopsy results confirmed herpesvirus, highlighting its importance in diagnosing eyelid conditions.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Dermatology
Background:
- Eyelid lesions in immunocompromised patients can present diagnostic challenges.
- Malignancy is often a primary concern for rapidly growing or ulcerated lesions.
Observation:
- A case study of an HIV-positive male patient presenting with a rapidly enlarging and ulcerated lower eyelid lesion.
- The lesion's appearance raised suspicion for a malignant neoplastic process.
Findings:
- Histopathological examination of the lesion revealed characteristic inclusions.
- These inclusions were consistent with a herpesvirus infection.
Implications:
- Herpesvirus infection should be included in the differential diagnosis for unusual eyelid lesions, particularly in HIV-positive individuals.
- This case underscores the need for thorough diagnostic evaluation of eyelid abnormalities in immunocompromised patients.