Related Experiment Video
Updated: Aug 9, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Successful treatment of massive pulmonary embolism with prolonged catheter-directed thrombolysis
Peter Kelly1, Niamh Carroll, Cliona Grant
1Department of Cardiology, Cork University Hospital, Wilton, Cork, Ireland. peterjwkelly50@hotmail.com
Abstract:
This is a case report of a young woman who presented with an extensive pulmonary embolism and echocardiographic evidence of right ventricular dysfunction. Although hemodynamically stable, the patient's clinical condition failed to improve with standard heparin anticoagulation. Successful local catheter-directed thrombolysis was performed over an extended period of 48 h with regular monitoring of response to therapy by computed tomography-pulmonary angiography and echocardiography. To our knowledge, treatment of a pulmonary embolism by catheter-directed thrombolytic infusion over an extended period of 48 h has not previously been described.
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