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Published on: January 23, 2018
Adamantinoma of tibia: a study of 12 cases
Saral S Desai1, Nirmala Jambhekar, Manish Agarwal
1Department of Pathology, Tata Memorial Hospital, Dr. Ernest Borges Road, Parel, Mumbai, India. saraldesai@hotmail.com
Background:
Adamantinoma is a rare tumor of long bones that can be mistaken for a carcinoma, and numerous other lesions such as myoepithelial tumor, malignant mixed tumor of bone, fibrous dysplasia/osteofibrous dysplasia, and vascular tumors.
Methods:
The histology and clinical features of 12 cases accrued from the surgical pathology files over a period of 23 years were analyzed.
Results:
Of the 12 cases, 4 were men and 8 women, with a mean age of 30 years. Radiologically the tumor presented as a lytic, eccentric, intracortical lesion in the tibia. The histology revealed epithelial islands with basaloid, spindle, and squamous features on a background of fibrotic stroma. Three patients came back with local recurrences, and one of them developed pulmonary metastasis.
Discussion:
In this article, an attempt is made to study the morphology, biology, and the differential diagnoses of adamantinoma of long bones.
