Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Encephalopathy associated with Hashimoto thyroiditis: pediatric perspective.

Nathan Watemberg1, Dalia Greenstein, Arie Levine

  • 1Pediatric Neurology Unit, Sackler School of Medicine, Tel Aviv University, Israel. nwatemberg@pol.net

Journal of Child Neurology
|March 23, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

STEP-CD study: ustekinumab use in paediatric Crohn's disease-a multicentre retrospective study from paediatric IBD Porto group of ESPGHAN.

European journal of pediatrics·2024
Same author

Word-Finding Difficulties as a Prominent Early Finding in a Later Diagnosis of Attention Deficit Hyperactivity Disorder.

Neuropediatrics·2023
Same author

Unfermented β-fructan Fibers Fuel Inflammation in Select Inflammatory Bowel Disease Patients.

Gastroenterology·2022
Same author

Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn Disease (the Speed-up Study): A Multicenter Study from the Pediatric IBD Porto Group of ESPGHAN.

Journal of pediatric gastroenterology and nutrition·2022
Same author

Outcomes and Predictors of Sustained Remission After Drug Withdrawal in Pediatric Crohn Disease.

Journal of pediatric gastroenterology and nutrition·2022
Same author

Metabolome Changes With Diet-Induced Remission in Pediatric Crohn's Disease.

Gastroenterology·2022
Same journal

Birmingham, 1963.

Journal of child neurology·2026
Same journal

Hyperintensity on Diffusion-Weighted Imaging in a MELAS Patient Does Not Necessarily Mean Cytotoxic Edema.

Journal of child neurology·2026
Same journal

Neuromuscular Symptoms of <i>ORAI1</i>-Related Immunodeficiency.

Journal of child neurology·2026
Same journal

Symptoms of Obsessive-Compulsive Disorder, Attention-Deficit/Hyperactivity Disorder, and Autism Spectrum Disorder in Children and Adolescents Attending a Headache Outpatient Clinic and School-Based Controls.

Journal of child neurology·2026
Same journal

Acute Encephalopathy From Central Nervous System Hemophagocytic Lymphohistiocytosis (CNS HLH) in X-Linked Lymphoproliferative Disease Type 1 (XLP-1).

Journal of child neurology·2026
Same journal

The Cost of Fear for Pediatric Neurologic Care.

Journal of child neurology·2026
See all related articles

Hashimoto encephalopathy, a neurologic complication of Hashimoto thyroiditis, presents with varied symptoms and is often underdiagnosed in children. Early recognition and corticosteroid treatment are crucial for patient recovery.

Area of Science:

  • Neurology
  • Endocrinology
  • Immunology

Background:

  • Neuropsychiatric symptoms are increasingly linked to Hashimoto thyroiditis in adults and children.
  • This condition, known as Hashimoto encephalopathy, can manifest acutely or gradually with neurological and psychiatric issues.
  • Its occurrence is independent of thyroid hormone levels.

Purpose of the Study:

  • To highlight the recognition and diagnosis of Hashimoto encephalopathy.
  • To emphasize the importance of physician awareness for timely diagnosis and treatment.
  • To discuss the potential diagnostic challenges and therapeutic approaches.

Main Methods:

  • Review of clinical presentations and diagnostic criteria for Hashimoto encephalopathy.
  • Discussion of underlying autoimmune and vasculitic mechanisms.

Related Experiment Videos

  • Analysis of diagnostic tools, including antibody testing, CSF, EEG, and neuroimaging.

    • Main Results:

    • Hashimoto encephalopathy diagnosis relies on detecting antithyroid antibodies, irrespective of antibody levels or thyroid status.
    • Standard diagnostic tests like CSF, EEG, and neuroimaging lack consistent findings.
    • Most patients show significant improvement with corticosteroid therapy.

    Conclusions:

    • Hashimoto encephalopathy is likely underdiagnosed, particularly in pediatric populations.
    • Increased physician awareness is vital for early identification and to prevent extensive work-ups.
    • Prompt corticosteroid treatment offers a highly effective therapeutic strategy.