Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Emergency laparotomy in patients with AIDS.

T Davidson1, T G Allen-Mersh, A J Miles

  • 1Surgical Unit, Westminster Hospital, London, UK.

The British Journal of Surgery
|August 1, 1991
PubMed
Summary

Emergency laparotomy in AIDS patients can be life-saving, particularly for cytomegalovirus (CMV) toxic megacolon. However, surgery offers less benefit for abdominal pain caused by atypical mycobacterial infection or lymphoma.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tools and methods for circular dichroism spectroscopy of proteins: a tutorial review.

Chemical Society reviews·2021
Same author

Consensus exercise identifying priorities for research in the field of general surgery of childhood in the UK.

BJS open·2021
Same author

The EuroSIDA study: 25 years of scientific achievements.

HIV medicine·2019
Same author

Correction to: CSF inflammatory markers and neurocognitive function after addition of maraviroc to monotherapy darunavir/ritonavir in stable HIV patients: the CINAMMON study.

Journal of neurovirology·2018
Same author

CSF inflammatory markers and neurocognitive function after addition of maraviroc to monotherapy darunavir/ritonavir in stable HIV patients: the CINAMMON study.

Journal of neurovirology·2017
Same author

Low levels of neurocognitive impairment detected in screening HIV-infected men who have sex with men: The MSM Neurocog Study.

International journal of STD & AIDS·2016

Area of Science:

  • Surgery
  • Infectious Diseases
  • Gastroenterology

Background:

  • Acquired Immunodeficiency Syndrome (AIDS) patients present unique challenges for emergency abdominal surgery.
  • Abdominal pathologies in AIDS patients are often linked to opportunistic infections and malignancies.

Purpose of the Study:

  • To review the presentation, operative management, and outcomes of emergency laparotomy in patients with AIDS.
  • To identify factors influencing surgical outcomes and survival in this population.

Main Methods:

  • Retrospective review of 28 AIDS patients undergoing emergency laparotomy.
  • Analysis of clinical, radiological, and diagnostic findings.
  • Evaluation of perioperative and long-term survival rates.

Related Experiment Videos

Main Results:

  • Common indications included toxic megacolon (n=6), small bowel obstruction (n=5), and peritonitis (n=9).
  • Frequent diagnoses were cytomegalovirus (CMV) colitis (n=7), intra-abdominal lymphoma (n=5), and appendicitis (n=5).
  • Perioperative mortality was 7%, with 6-month survival at 48%. Earlier intervention for CMV toxic megacolon may reduce mortality.

Conclusions:

  • Emergency laparotomy can provide palliation in carefully selected AIDS patients.
  • Surgical outcomes are less favorable for abdominal pain due to atypical mycobacterial infection or lymphoma.
  • Timely intervention, especially for CMV-related conditions, may improve survival rates.