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Updated: Aug 9, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Stent-graft for recurrent melioidosis mycotic aortic aneurysm
Ser Y Lee1, Yoong K Sin, Asok Kurup
1Singapore Health Services Pte Ltd., 11 Third Hospital Avenue, SNEC Building, Singapore. lee.ser.yee@singhealth.com.sg
Abstract:
Melioidosis is a tropical disease caused by Burkholderia pseudomallei and is prevalent in South East Asia and Northern Australia. It can infect any organ system and is potentially deadly. Melioidosis causing a mycotic aneurysm of the aorta is rare. We present a patient with a melioidosis mycotic aneurysm of the descending aorta presenting with fever and right pleural effusion, managed successfully with initial Dacron graft repair with staged omental reinforcement, and subsequent endovascular stent grafting of a late anastomotic leak.
Insights
Melioidosis, a tropical disease, can cause rare aortic aneurysms. This case highlights successful surgical and endovascular management of a mycotic aneurysm caused by Burkholderia pseudomallei.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Medical Microbiology
Background:
- Melioidosis is an infectious disease endemic in tropical regions, caused by Burkholderia pseudomallei.
- The bacterium can infect multiple organ systems, leading to severe and potentially fatal complications.
- Mycotic aneurysms, particularly of the aorta, are an uncommon manifestation of melioidosis.
Observation:
- A patient presented with fever and right pleural effusion.
- The patient was diagnosed with a mycotic aneurysm of the descending aorta due to melioidosis.
- This presentation is a rare occurrence of the disease.
Findings:
- Successful initial management involved Dacron graft repair with omental reinforcement.
- A late anastomotic leak was subsequently managed with endovascular stent grafting.
- This combined approach proved effective in treating the complex aortic aneurysm.
Implications:
- This case demonstrates a viable treatment strategy for rare melioidosis-induced aortic aneurysms.
- It highlights the importance of considering melioidosis in endemic areas for patients with unexplained fevers and vascular complications.
- The successful dual-modality treatment offers insights for managing similar complex vascular infections.
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